Patulin is a mycotoxin produced by certain species of Aspergillus
Patulin is a mycotoxin produced by certain species of Aspergillus.
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MI, USA). 4-Hydroxytamoxifen (4-OHT) was purchased from Sigma-Aldrich Biotechnology (St. Louis, MO, USA). Culture media and its supplements containing antibiotics, and fetal bovine serum (FBS) were purchased from Gibco Invitrogen Corporation (Carlsbad, CA, USA). The primary antibodies for acetyl-H3, acetyl-H4, Atg5, Atg7, β-actin, beclin-1, caspase 7, caspase 9, Cdc2, cyclin A, cyclin B1, cyclin D1, cyclin E, cytochrome c, HDACs, LC3, and p21 were purchased from Cell Signaling Technology (Beverly, MA, USA); Bax, Bcl-2, Cdk4, Cdk6, Cdk2, histone H1, poly(ADP-ribose) polymerase (PARP), and p27 antibodies were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). The Annexin V-FITC apoptosis detection kit I was purchased from BD Biosciences (San Diego, CA, USA). All other chemicals were purchased from Sigma-Aldrich.. evoked an innate immune response that was characteristic for viral. Although as mentioned above, authors believe in gradualness
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